Imbalance of Chemokines and Cytokines in the Bone Marrow Microenvironment of Children with B-Cell Acute Lymphoblastic Leukemia

In the hematopoietic microenvironment, leukemic cells secrete factors that imbalanced chemokine and cytokine production. However, the network of soluble immunological molecules in the bone marrow microenvironment of acute lymphoblastic leukemia (ALL) remains underexplored. Herein, we evaluated the l...

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Main Authors: Fábio Magalhães-Gama, Marlon Wendell Athaydes Kerr, Nilberto Dias de Araújo, Hiochelson Najibe Santos Ibiapina, Juliana Costa Ferreira Neves, Fabíola Silva Alves Hanna, Lilyane de Amorim Xabregas, Maria Perpétuo Socorro Sampaio Carvalho, Eliana Brasil Alves, Andréa Monteiro Tarragô, Olindo Assis Martins-Filho, Andréa Teixeira-Carvalho, Adriana Malheiro, Allyson Guimarães da Costa
Format: Article
Language:English
Published: Hindawi Limited 2021-01-01
Series:Journal of Oncology
Online Access:http://dx.doi.org/10.1155/2021/5530650