Prophylactic and Therapeutic Breast Conservation in BRCA1/2 Mutation Carriers

Breast-conserving therapy (BCT) for sporadic breast cancer has been widely accepted by surgeons and patients alike. While BCT is associated with a higher risk of ipsilateral breast tumor recurrence (IBTR), it has not been shown to decrease overall survival (OS) in comparison with mastectomy. Many wo...

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Bibliographic Details
Main Authors: Randal L. Croshaw, Megan L. Marshall, Tesha L. Williams, Kathleen M. Erb, Thomas B. Julian
Format: Article
Language:English
Published: Hindawi Limited 2011-01-01
Series:International Journal of Breast Cancer
Online Access:http://dx.doi.org/10.4061/2011/481563