Erythropoietin Protects Against Lipopolysaccharide-Induced Microgliosis and Abnormal Granule Cell Development in the Ovine Fetal Cerebellum

Erythropoietin Protects Against Lipopolysaccharide-Induced Microgliosis and Abnormal Granule Cell Development in the Ovine Fetal Cerebellum

Erythropoietin (EPO) ameliorates inflammation-induced injury in cerebral white matter (WM). However, effects of inflammation on the cerebellum and neuroprotective effects of EPO are unknown. Our aims were to determine: (i) whether lipopolysaccharide (LPS)-induced intrauterine inflammation causes inj...

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Bibliographic Details
Main Authors: Annie R. A. McDougall, Nadia Hale, Sandra Rees, Richard Harding, Robert De Matteo, Stuart B. Hooper, Mary Tolcos
Format: Article
Language:English
Published: Frontiers Media S.A. 2017-07-01
Series:Frontiers in Cellular Neuroscience
Subjects:
chorioamnionitis
inflammation
brain development
cell proliferation
neuronal migration
Online Access:http://journal.frontiersin.org/article/10.3389/fncel.2017.00224/full

Internet

http://journal.frontiersin.org/article/10.3389/fncel.2017.00224/full

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