The anti-apoptotic factor Che-1/AATF links transcriptional regulation, cell cycle control, and DNA damage response

<p>Abstract</p> <p>Che-1 is a RNA polymerase II binding protein involved in the transcriptional regulation of E2F target genes and in cell proliferation. Recently, it has been shown that Che-1 accumulates in cells responding to genotoxic agents such as Doxorubicin and ionizing radi...

Full description

Bibliographic Details
Main Authors: Fanciulli Maurizio, Passananti Claudio
Format: Article
Language:English
Published: BMC 2007-07-01
Series:Cell Division
Online Access:http://www.celldiv.com/content/2/1/21