Inflammation-associated regulation of RGS in astrocytes and putative implication in neuropathic pain

Inflammation-associated regulation of RGS in astrocytes and putative implication in neuropathic pain

Abstract Background Regulators of G-protein signaling (RGS) are major physiological modulators of G-protein-coupled receptors (GPCR) signaling. Several GPCRs expressed in both neurons and astrocytes participate in the central control of pain processing, and the reduced efficacy of analgesics in neur...

Full description

Bibliographic Details
Main Authors: Pierre J. Doyen, Maxime Vergouts, Amandine Pochet, Nathalie Desmet, Sabien van Neerven, Gary Brook, Emmanuel Hermans
Format: Article
Language:English
Published: BMC 2017-10-01
Series:Journal of Neuroinflammation
Subjects:
Astrocytes
Glial cells
Neuropathic pain
Inflammation
Regulator of G-protein signaling
Cytokines
Online Access:http://link.springer.com/article/10.1186/s12974-017-0971-x

Internet

http://link.springer.com/article/10.1186/s12974-017-0971-x

Similar Items