Clinical relevance of tumor cells with stem-like properties in pediatric brain tumors.

<h4>Background</h4>Primitive brain tumors are the leading cause of cancer-related death in children. Tumor cells with stem-like properties (TSCs), thought to account for tumorigenesis and therapeutic resistance, have been isolated from high-grade gliomas in adults. Whether TSCs are a com...

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Main Authors: Cécile Thirant, Barbara Bessette, Pascale Varlet, Stéphanie Puget, Josette Cadusseau, Silvina Dos Reis Tavares, Jeanne-Marie Studler, David Carlos Silvestre, Aurélie Susini, Chiara Villa, Catherine Miquel, Alexandra Bogeas, Anne-Laure Surena, Amélia Dias-Morais, Nadine Léonard, Françoise Pflumio, Ivan Bièche, François D Boussin, Christian Sainte-Rose, Jacques Grill, Catherine Daumas-Duport, Hervé Chneiweiss, Marie-Pierre Junier
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/21297991/?tool=EBI