The STING1 network regulates autophagy and cell death

Abstract Cell death and immune response are at the core of life. In past decades, the endoplasmic reticulum (ER) protein STING1 (also known as STING or TMEM173) was found to play a fundamental role in the production of type I interferons (IFNs) and pro-inflammatory cytokines in response to DNA deriv...

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Bibliographic Details
Main Authors: Ruoxi Zhang, Rui Kang, Daolin Tang
Format: Article
Language:English
Published: Nature Publishing Group 2021-06-01
Series:Signal Transduction and Targeted Therapy
Online Access:https://doi.org/10.1038/s41392-021-00613-4