Novel functional MAR elements of double minute chromosomes in human ovarian cells capable of enhancing gene expression.

Novel functional MAR elements of double minute chromosomes in human ovarian cells capable of enhancing gene expression.

Double minute chromosomes or double minutes (DMs) are cytogenetic hallmarks of extrachromosomal genomic amplification and play a critical role in tumorigenesis. Amplified copies of oncogenes in DMs have been associated with increased growth and survival of cancer cells but DNA sequences in DMs which...

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Bibliographic Details
Main Authors: Yan Jin, Zheng Liu, Wei Cao, Xinying Ma, Yihui Fan, Yang Yu, Jing Bai, Feng Chen, Jesusa Rosales, Ki-Young Lee, Songbin Fu
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/22319568/?tool=EBI

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https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/22319568/?tool=EBI

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