Genomic loss in environmental and isogenic morphotype isolates of Burkholderia pseudomallei is associated with intracellular survival and plaque-forming efficiency.

Genomic loss in environmental and isogenic morphotype isolates of Burkholderia pseudomallei is associated with intracellular survival and plaque-forming efficiency.

<h4>Background</h4>Burkholderia pseudomallei is an environmental bacterium that causes melioidosis. A facultative intracellular pathogen, B. pseudomallei can induce multinucleated giant cells (MNGCs) leading to plaque formation in vitro. B. pseudomallei can switch colony morphotypes unde...

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Bibliographic Details
Main Authors: Natnaree Saiprom, Tanes Sangsri, Sarunporn Tandhavanant, Sineenart Sengyee, Rungnapa Phunpang, Anucha Preechanukul, Uriwan Surin, Apichai Tuanyok, Ganjana Lertmemongkolchai, Wasun Chantratita, T Eoin West, Narisara Chantratita
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2020-09-01
Series:PLoS Neglected Tropical Diseases
Online Access:https://doi.org/10.1371/journal.pntd.0008590

Internet

https://doi.org/10.1371/journal.pntd.0008590

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