Beta-catenin signaling regulates barrier-specific gene expression in circumventricular organ and ocular vasculatures

The brain, spinal cord, and retina are supplied by capillaries that do not permit free diffusion of molecules between serum and parenchyma, a property that defines the blood-brain and blood-retina barriers. Exceptions to this pattern are found in circumventricular organs (CVOs), small midline brain...

Full description

Bibliographic Details
Main Authors: Yanshu Wang, Mark F Sabbagh, Xiaowu Gu, Amir Rattner, John Williams, Jeremy Nathans
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2019-04-01
Series:eLife
Subjects:
Wnt
Online Access:https://elifesciences.org/articles/43257