Vaccine-induced boosting of influenza virus-specific CD4 T cells in younger and aged humans.

Vaccine-induced boosting of influenza virus-specific CD4 T cells in younger and aged humans.

Current yearly influenza virus vaccines induce strain-specific neutralizing antibody (NAb) responses providing protective immunity to closely matched viruses. However, these vaccines are often poorly effective in high-risk groups such as the elderly and challenges exist in predicting yearly or emerg...

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Bibliographic Details
Main Authors: Douglas V Dolfi, Kathleen D Mansfield, Raj K Kurupati, Senthil Kannan, Susan A Doyle, Hildegund C J Ertl, Kenneth E Schmader, E John Wherry
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3796569?pdf=render

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http://europepmc.org/articles/PMC3796569?pdf=render

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