Defining the ABC of gene essentiality in streptococci

Abstract Background Utilising next generation sequencing to interrogate saturated bacterial mutant libraries provides unprecedented information for the assignment of genome-wide gene essentiality. Exposure of saturated mutant libraries to specific conditions and subsequent sequencing can be exploite...

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Bibliographic Details
Main Authors: Amelia R. L. Charbonneau, Oliver P. Forman, Amy K. Cain, Graham Newland, Carl Robinson, Mike Boursnell, Julian Parkhill, James A. Leigh, Duncan J. Maskell, Andrew S. Waller
Format: Article
Language:English
Published: BMC 2017-05-01
Series:BMC Genomics
Subjects:
Online Access:http://link.springer.com/article/10.1186/s12864-017-3794-3