Regulation of hippocampal and behavioral excitability by cyclin-dependent kinase 5.

Cyclin-dependent kinase 5 (Cdk5) is a proline-directed serine/threonine kinase that has been implicated in learning, synaptic plasticity, neurotransmission, and numerous neurological disorders. We previously showed that conditional loss of Cdk5 in adult mice enhanced hippocampal learning and plastic...

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Bibliographic Details
Main Authors: Ammar H Hawasli, Della Koovakkattu, Kanehiro Hayashi, Anne E Anderson, Craig M Powell, Christopher M Sinton, James A Bibb, Donald C Cooper
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2009-06-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2695674?pdf=render