Hepatitis B Virus-Like Particle: Targeted Delivery of Plasmid Expressing Short Hairpin RNA for Silencing the <i>Bcl-2</i> Gene in Cervical Cancer Cells

Hepatitis B Virus-Like Particle: Targeted Delivery of Plasmid Expressing Short Hairpin RNA for Silencing the <i>Bcl-2</i> Gene in Cervical Cancer Cells

Gene therapy research has advanced to clinical trials, but it is hampered by unstable nucleic acids packaged inside carriers and there is a lack of specificity towards targeted sites in the body. This study aims to address gene therapy limitations by encapsidating a plasmid synthesizing a short hair...

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Bibliographic Details
Main Authors: Made Angga Akwiditya, Chean Yeah Yong, Mohd Termizi Yusof, Abdul Razak Mariatulqabtiah, Kok Lian Ho, Wen Siang Tan
Format: Article
Language:English
Published: MDPI AG 2021-02-01
Series:International Journal of Molecular Sciences
Subjects:
short interference RNA
virus-like particle
anti-apoptotic <i>Bcl-2</i>
plasmid delivery
folic acid
Online Access:https://www.mdpi.com/1422-0067/22/5/2320

Internet

https://www.mdpi.com/1422-0067/22/5/2320

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