Immune Cytolytic Activity for Comprehensive Understanding of Immune Landscape in Hepatocellular Carcinoma

Immune Cytolytic Activity for Comprehensive Understanding of Immune Landscape in Hepatocellular Carcinoma

Cytolytic activity score (CYT), defined by granzyme A and perforin expression, is a useful marker for underlying immunity. We hypothesized that CYT-high hepatocellular carcinomas (HCCs) have stronger immunogenicity and favorable tumor microenvironments, which would result in better clinical outcomes...

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Bibliographic Details
Main Authors: Hideo Takahashi, Tsutomu Kawaguchi, Li Yan, Xuan Peng, Qianya Qi, Luc G.T. Morris, Timothy A. Chan, Allan Tsung, Eigo Otsuji, Kazuaki Takabe
Format: Article
Language:English
Published: MDPI AG 2020-05-01
Series:Cancers
Subjects:
hepatocellular carcinoma
cytolytic activity
tumor infiltrating lymphocyte
TCGA
Online Access:https://www.mdpi.com/2072-6694/12/5/1221

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https://www.mdpi.com/2072-6694/12/5/1221

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