The preventive effect of total saponins from Panax japonicus on inflammation and insulin resistance in adipose tissue of mice induced by a high-fat diet

The preventive effect of total saponins from Panax japonicus on inflammation and insulin resistance in adipose tissue of mice induced by a high-fat diet

We aimed to investigate the effects of total saponins from Panax japonicus (TSPJ) on adipocyte inflammation and insulin resistance induced by a high-fat diet (HFD). Moreover, its underlying mechanism was further explored. In vivo, we found that TSPJ inhibited the activation of NF-κB and increase the...

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Bibliographic Details
Main Authors: Yue Shi, Zhengtai Liu, Liyue Gai, Yan Gao, Yumin He, Chaoqi Liu, Changcheng Zhang, Gang Zhou, Ding Yuan, Chengfu Yuan
Format: Article
Language:English
Published: Elsevier 2021-03-01
Series:Journal of Functional Foods
Subjects:
Adipose tissue inflammation
AMPK
Total saponins from Panax japonicus
High-fat diet
Insulin resistance
NF-κB
Online Access:http://www.sciencedirect.com/science/article/pii/S1756464621000189

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http://www.sciencedirect.com/science/article/pii/S1756464621000189

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