Recombinant Human Soluble Thrombomodulin Suppresses Monocyte Adhesion by Reducing Lipopolysaccharide-Induced Endothelial Cellular Stiffening

Recombinant Human Soluble Thrombomodulin Suppresses Monocyte Adhesion by Reducing Lipopolysaccharide-Induced Endothelial Cellular Stiffening

Endothelial cellular stiffening has been observed not only in inflamed cultured endothelial cells but also in the endothelium of atherosclerotic regions, which is an underlying cause of monocyte adhesion and accumulation. Although recombinant soluble thrombomodulin (rsTM) has been reported to suppre...

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Bibliographic Details
Main Authors: Takayuki Okamoto, Eiji Kawamoto, Haruki Usuda, Tetsuya Tanaka, Tetsuro Nikai, Kunihiro Asanuma, Koji Suzuki, Motomu Shimaoka, Koichiro Wada
Format: Article
Language:English
Published: MDPI AG 2020-07-01
Series:Cells
Subjects:
endothelial cells
cellular stiffness
thrombomodulin
cell adhesion
gap junctions
Online Access:https://www.mdpi.com/2073-4409/9/8/1811

Internet

https://www.mdpi.com/2073-4409/9/8/1811

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