Rapid fabrication of vascularized and innervated cell-laden bone models with biomimetic intrafibrillar collagen mineralization

Rapid fabrication of vascularized and innervated cell-laden bone models with biomimetic intrafibrillar collagen mineralization

Bone tissue is a complex organic-inorganic nanocomposite and strategies that replicate the characteristics of bone tissue are scarce. Here the authors demonstrate the deposition of nanoscale apatite in collagen embedded with mesenchymal, vascular and nerve cells, using a protein-guided biomineraliza...

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Bibliographic Details
Main Authors: Greeshma Thrivikraman, Avathamsa Athirasala, Ryan Gordon, Limin Zhang, Raymond Bergan, Douglas R. Keene, James M. Jones, Hua Xie, Zhiqiang Chen, Jinhui Tao, Brian Wingender, Laurie Gower, Jack L. Ferracane, Luiz E. Bertassoni
Format: Article
Language:English
Published: Nature Publishing Group 2019-08-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-019-11455-8

Internet

https://doi.org/10.1038/s41467-019-11455-8

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