Oxidative Asymmetric Formal Aza-Diels–Alder Reactions of Tetrahydro-β-carboline with Enones in the Synthesis of Indoloquinolizidine-2-ones

Oxidative Asymmetric Formal Aza-Diels–Alder Reactions of Tetrahydro-β-carboline with Enones in the Synthesis of Indoloquinolizidine-2-ones

Ru-catalyzed tandem amine oxidative dehydrogenation/formal aza-Diels–Alder reaction for enantio- and diastereoselective synthesis of indoloquinolizidine-2-ones from tetrahydro-β-carbolines and α,β-unsaturated ketones is described. The reaction proceeds via tande...

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Bibliographic Details
Main Authors: Xiang Wu, Shi-Bao Zhao, Lang-Lang Zheng, You-Gui Li
Format: Article
Language:English
Published: MDPI AG 2018-09-01
Series:Molecules
Subjects:
aza-Diels–Alder reaction
indoloquinolizidine-2-ones
enantioselective catalysis
cooperative catalysis
ruthenium
Online Access:http://www.mdpi.com/1420-3049/23/9/2228

Internet

http://www.mdpi.com/1420-3049/23/9/2228

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