Activation of Melanocortin Receptors MC1 and MC5 Attenuates Retinal Damage in Experimental Diabetic Retinopathy

We hypothesize that melanocortin receptors (MC) could activate tissue protective circuit in a model of streptozotocin- (STZ-) induced diabetic retinopathy (DR) in mice. At 12–16 weeks after diabetes induction, fluorescein angiography (FAG) revealed an approximate incidence of 80% microvascular chang...

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Bibliographic Details
Main Authors: S. Rossi, R. Maisto, C. Gesualdo, M. C. Trotta, F. Ferraraccio, M. K. Kaneva, S. J. Getting, E. Surace, F. Testa, F. Simonelli, P. Grieco, F. Merlino, M. Perretti, M. D’Amico, C. Di Filippo
Format: Article
Language:English
Published: Hindawi Limited 2016-01-01
Series:Mediators of Inflammation
Online Access:http://dx.doi.org/10.1155/2016/7368389