Early escitalopram administration as a preemptive treatment strategy against spasticity after contusive spinal cord injury in rats

Early escitalopram administration as a preemptive treatment strategy against spasticity after contusive spinal cord injury in rats

Abstract In the majority of spinal cord injury (SCI) patients, spasticity develops in the subacute phase and chronically persists with muscle hypertonia. Among various pathological conditions underlying spasticity, upregulated expression of 5-HT receptors (5-HTR) on the spinal motor neurons due to 5...

Full description

Bibliographic Details
Main Authors: Youngjae Ryu, Toru Ogata, Motoshi Nagao, Yasuhiro Sawada, Ryohei Nishimura, Naoki Fujita
Format: Article
Language:English
Published: Nature Publishing Group 2021-03-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-021-85961-5

Internet

https://doi.org/10.1038/s41598-021-85961-5

Similar Items