HIF-1α Provokes Delayed Neutrophil Apoptosis by Decreasing 24P3 Expression and Intracellular Iron Content
Neutrophil apoptosis is delayed in medical conditions associated to anoxia or hypoxia, prolonging tissue destruction and fostering the inflammation. Hypoxia Inducible Factor-1α (HIF-1α), is a main regulator of delayed neutrophil apoptosis but the mechanism of action is poorly characterized. Neutroph...
Main Authors: | , , , |
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Format: | Article |
Language: | English |
Published: |
SAGE Publishing
2014-01-01
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Series: | European Journal of Inflammation |
Online Access: | https://doi.org/10.1177/1721727X1401200106 |