Prediction of Conserved Peptides of <i>Paracoccidioides</i> for Interferon-γ Release Assay: The First Step in the Development of a Lab-Based Approach for Immunological Assessment during Antifungal Therapy

Prediction of Conserved Peptides of <i>Paracoccidioides</i> for Interferon-γ Release Assay: The First Step in the Development of a Lab-Based Approach for Immunological Assessment during Antifungal Therapy

Impaired antigen-specific cell-mediated immunity (CMI) is a primary immunological disturbance observed in individuals that develop paracoccidioidomycosis (PCM) after exposure to <i>Paracoccidioides</i> spp. Restoration of <i>Paracoccidioides</i>-specific CMI is crucial to sto...

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Bibliographic Details
Main Authors: Sarah Brena Aparecida Rosa, Bárbara Guimarães Csordas, Sandra Maria do Valle Leone de Oliveira, Amanda Ribeiro dos Santos, Anamaria Mello Miranda Paniago, James Venturini
Format: Article
Language:English
Published: MDPI AG 2020-12-01
Series:Journal of Fungi
Subjects:
cellular immunity
paracoccidioidomycosis
in silico prediction
MHC II
IFN-γ
<i>Paracoccidioides brasiliensis</i>
Online Access:https://www.mdpi.com/2309-608X/6/4/379

Internet

https://www.mdpi.com/2309-608X/6/4/379

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