Baicalein alleviates tubular-interstitial nephritis in vivo and in vitro by down-regulating NF-κB and MAPK pathways

Baicalein alleviates tubular-interstitial nephritis in vivo and in vitro by down-regulating NF-κB and MAPK pathways

Tubular-interstitial nephritis (TIN) is characterized by tubular cell damage and inflammatory lesions of kidneys. Baicalein (BAI) is a flavonoid compound found in the roots of Scutellaria baicalensis Georgi. The present study was undertaken to explore the anti-inflammatory and anti-oxidative effects...

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Bibliographic Details
Main Authors: Yan Chen, Yu Zheng, Zhihong Zhou, Jinjun Wang
Format: Article
Language:English
Published: Associação Brasileira de Divulgação Científica 2018-08-01
Series:Brazilian Journal of Medical and Biological Research
Subjects:
Tubular-interstitial nephritis
Baicalein
Lipopolysaccharide
Anti-inflammatory effects
NF-κB pathway
MAPK pathway
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2018001000606&lng=en&tlng=en

Internet

http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2018001000606&lng=en&tlng=en

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