Fluorescence lifetime imaging of alterations to cellular metabolism by domain 2 of the hepatitis C virus core protein.

Fluorescence lifetime imaging of alterations to cellular metabolism by domain 2 of the hepatitis C virus core protein.

Hepatitis C virus (HCV) co-opts hepatic lipid pathways to facilitate its pathogenesis. The virus alters cellular lipid biosynthesis and trafficking, and causes an accumulation of lipid droplets (LDs) that gives rise to hepatic steatosis. Little is known about how these changes are controlled at the...

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Main Authors: Nirmal Mazumder, Rodney K Lyn, Ragunath Singaravelu, Andrew Ridsdale, Douglas J Moffatt, Chih-Wei Hu, Han-Ruei Tsai, John McLauchlan, Albert Stolow, Fu-Jen Kao, John Paul Pezacki
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3691201?pdf=render

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http://europepmc.org/articles/PMC3691201?pdf=render

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