PTEN inhibits BMI1 function independently of its phosphatase activity
<p>Abstract</p> <p>Background</p> <p><it>PTEN </it>is the second most mutated tumor suppressor gene other than p53. It suppresses tumorigenesis by dephosphorylating phosphatidylinositol (3,4,5)-triphosphate (<b>PIP3</b>) to phosphatidylinositol (...
| Main Authors: | , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
BMC
2009-11-01
|
| Series: | Molecular Cancer |
| Online Access: | http://www.molecular-cancer.com/content/8/1/98 |