LAT region factors mediating differential neuronal tropism of HSV-1 and HSV-2 do not act in trans.

LAT region factors mediating differential neuronal tropism of HSV-1 and HSV-2 do not act in trans.

After HSV infection, some trigeminal ganglion neurons support productive cycle gene expression, while in other neurons the virus establishes a latent infection. We previously demonstrated that HSV-1 and HSV-2 preferentially establish latent infection in A5+ and KH10+ sensory neurons, respectively, a...

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Bibliographic Details
Main Authors: Andrea S Bertke, Kathleen Apakupakul, AyeAye Ma, Yumi Imai, Anne M Gussow, Kening Wang, Jeffrey I Cohen, David C Bloom, Todd P Margolis
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3534042?pdf=render

Internet

http://europepmc.org/articles/PMC3534042?pdf=render

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