Manipulating the NF-κB pathway in macrophages using mannosylated, siRNA-delivering nanoparticles can induce immunostimulatory and tumor cytotoxic functions

Manipulating the NF-κB pathway in macrophages using mannosylated, siRNA-delivering nanoparticles can induce immunostimulatory and tumor cytotoxic functions

Ryan A Ortega,1–3 Whitney Barham,3 Kavya Sharman,4 Oleg Tikhomirov,3 Todd D Giorgio,1–3 Fiona E Yull3 1Department of Biomedical Engineering, Vanderbilt University, 2Vanderbilt Institute for Nanoscale Science and Engineering, 3Department of Cancer Biology, Vanderbilt-Ingram Cance...

Full description

Bibliographic Details
Main Authors: Ortega RA, Barham W, Sharman K, Tikhomirov O, Giorgio TD, Yull FE
Format: Article
Language:English
Published: Dove Medical Press 2016-05-01
Series:International Journal of Nanomedicine
Subjects:
Targeted nanoparticles
cancer immunology
tumor associated macrophages
NF-κB pathway
siRNA
Online Access:https://www.dovepress.com/manipulating-the-nf-kappab-pathway-in-macrophages-using-mannosylated-s-peer-reviewed-article-IJN

Internet

https://www.dovepress.com/manipulating-the-nf-kappab-pathway-in-macrophages-using-mannosylated-s-peer-reviewed-article-IJN

Similar Items