Mapping genetically compensatory pathways from synthetic lethal interactions in yeast.
Synthetic lethal genetic interaction analysis has been successfully applied to predicting the functions of genes and their pathway identities. In the context of synthetic lethal interaction data alone, the global similarity of synthetic lethal interaction patterns between two genes is used to predic...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
| Published: |
Public Library of Science (PLoS)
2008-04-01
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| Series: | PLoS ONE |
| Online Access: | http://europepmc.org/articles/PMC2275788?pdf=render |