Intestinal alkaline phosphatase inhibits the translocation of bacteria of gut-origin in mice with peritonitis: mechanism of action.

Exogenous intestinal alkaline phosphatase (IAP), an enzyme produced endogenously at the brush edge of the intestinal mucosa, may mitigate the increase in aberrant intestinal permeability increased during sepsis. The aim of this study was to test the efficacy of the inhibitory effect of IAP on acute...

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Bibliographic Details
Main Authors: Wei Wang, Shan-Wen Chen, Jing Zhu, Shuai Zuo, Yuan-Yuan Ma, Zi-Yi Chen, Jun-Ling Zhang, Guo-Wei Chen, Yu-Cun Liu, Peng-Yuan Wang
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4422672?pdf=render