A natural plasmid uniquely encodes two biosynthetic pathways creating a potent anti-MRSA antibiotic.

A natural plasmid uniquely encodes two biosynthetic pathways creating a potent anti-MRSA antibiotic.

Understanding how complex antibiotics are synthesised by their producer bacteria is essential for creation of new families of bioactive compounds. Thiomarinols, produced by marine bacteria belonging to the genus Pseudoalteromonas, are hybrids of two independently active species: the pseudomonic acid...

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Bibliographic Details
Main Authors: Daisuke Fukuda, Anthony S Haines, Zhongshu Song, Annabel C Murphy, Joanne Hothersall, Elton R Stephens, Rachel Gurney, Russell J Cox, John Crosby, Christine L Willis, Thomas J Simpson, Christopher M Thomas
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-03-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3069032?pdf=render

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http://europepmc.org/articles/PMC3069032?pdf=render

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