Gene expression alterations in the medial prefrontal cortex and blood cells in a mouse model of depression during menopause

Aims: The prevalence of major depressive disorder (MDD) is higher in women than in men, and this may be due to the decline in estrogen levels that occurs during the menopausal transition. We studied the biological alterations in the medial prefrontal cortex (mPFC), which is a region that is highly i...

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Bibliographic Details
Main Authors: Shigeo Miyata, Masashi Kurachi, Noriko Sakurai, Yuchio Yanagawa, Yasuki Ishizaki, Masahiko Mikuni, Masato Fukuda
Format: Article
Language:English
Published: Elsevier 2016-12-01
Series:Heliyon
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2405844016306818