Immunization with an ApoB-100 Related Peptide Vaccine Attenuates Angiotensin-II Induced Hypertension and Renal Fibrosis in Mice.

Immunization with an ApoB-100 Related Peptide Vaccine Attenuates Angiotensin-II Induced Hypertension and Renal Fibrosis in Mice.

Recent studies suggest the potential involvement of CD8+ T cells in the pathogenesis of murine hypertension. We recently reported that immunization with apoB-100 related peptide, p210, modified CD8+ T cell function in angiotensin II (AngII)-infused apoE (-/-) mice. In this study, we hypothesized tha...

Full description

Bibliographic Details
Main Authors: Tomoyuki Honjo, Kuang-Yuh Chyu, Paul C Dimayuga, Wai Man Lio, Juliana Yano, Portia Trinidad, Xiaoning Zhao, Jianchang Zhou, Bojan Cercek, Prediman K Shah
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4486456?pdf=render

Internet

http://europepmc.org/articles/PMC4486456?pdf=render

Similar Items