Gene-based multiple regression association testing for combined examination of common and low frequency variants in quantitative trait analysis

Multi-marker methods for genetic association analysis can be performed for common and low frequency SNPs to improve power. Regression models are an intuitive way to formulate multi-marker tests. In previous studies we evaluated regression-based multi-marker tests for common SNPs, and through identif...

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Bibliographic Details
Main Authors: Yun Joo eYoo, Lei eSun, Shelley B. Bull
Format: Article
Language:English
Published: Frontiers Media S.A. 2013-11-01
Series:Frontiers in Genetics
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fgene.2013.00233/full