Eosinophilic Upper Airway Inflammation in a Murine Model Using an Adoptive Transfer System Induces Hyposmia and Epithelial Layer Injury with Convex Lesions

Eosinophilic Upper Airway Inflammation in a Murine Model Using an Adoptive Transfer System Induces Hyposmia and Epithelial Layer Injury with Convex Lesions

Background: Chronic rhinosinusitis with nasal polyps (CRSwNP) is a refractory upper airway disease, accompanied mainly by eosinophilia and/or asthma. In addition, the disease correlates with a high rate of hyposmia, following a marked infiltration of eosinophils into the inflamed site, the paranasal...

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Bibliographic Details
Main Authors: Akira Kanda, Kenji Kondo, Naoki Hosaka, Yoshiki Kobayashi, Dan Van Bui, Yasutaka Yun, Kensuke Suzuki, Shunsuke Sawada, Mikiya Asako, Akihiko Nakamura, Koichi Tomoda, Yoshiko Sakata, Koji Tsuta, David Dombrowicz, Hideyuki Kawauchi, Shigeharu Fujieda, Hiroshi Iwai
Format: Article
Language:English
Published: MDPI AG 2019-02-01
Series:Medical Sciences
Subjects:
allergic rhinitis
chronic rhino sinusitis
nasal poly
eosinophil
hyposmia
Online Access:https://www.mdpi.com/2076-3271/7/2/22

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