Th2-activated eosinophils release Th1 cytokines that modulate allergic inflammation

by Akira Kanda, Sébastien Fleury, Yoshiki Kobayashi, Koichi Tomoda, Valérie Julia, David Dombrowicz
Published 2015-09-01

Saturated Fatty Acids Promote GDF15 Expression in Human Macrophages through the PERK/eIF2/CHOP Signaling Pathway

by Laurent L’homme, Benan Pelin Sermikli, Bart Staels, Jacques Piette, Sylvie Legrand-Poels, David Dombrowicz
Published 2020-12-01

A functional gammadeltaTCR/CD3 complex distinct from gammadeltaT cells is expressed by human eosinophils.

by Fanny Legrand, Virginie Driss, Gaëtane Woerly, Sylvie Loiseau, Emmanuel Hermann, Jean-Jacques Fournié, Laurent Héliot, Virginie Mattot, Fabrice Soncin, Marie-Lise Gougeon, David Dombrowicz, Monique Capron
Published 2009-06-01

Beneficial metabolic effects of rapamycin are associated with enhanced regulatory cells in diet-induced obese mice.

by Kassem Makki, Solenne Taront, Olivier Molendi-Coste, Emmanuel Bouchaert, Bernadette Neve, Elodie Eury, Stéphane Lobbens, Myriam Labalette, Hélène Duez, Bart Staels, David Dombrowicz, Philippe Froguel, Isabelle Wolowczuk
Published 2014-01-01

Increased CD69 expression on activated eosinophils in eosinophilic chronic rhinosinusitis correlates with clinical findings

by Yasutaka Yun, Akira Kanda, Yoshiki Kobayashi, Dan Van Bui, Kensuke Suzuki, Shunsuke Sawada, Kazuyasu Baba, Masao Yagi, Mikiya Asako, Haruka Okazaki, Hiroki Ikeda, Shigeki Kawamura, Akihiko Nakamura, David Dombrowicz, Koichi Tomoda, Hiroshi Iwai
Published 2020-04-01

A Novel Approach for Investigating Upper Airway Hyperresponsiveness Using Micro-CT in Eosinophilic Upper Airway Inflammation such as Allergic Rhinitis Model

by Dan Van Bui, Akira Kanda, Yoshiki Kobayashi, Yoshiko Sakata, Yumiko Kono, Yoshiyuki Kamakura, Takao Jinno, Yasutaka Yun, Kensuke Suzuki, Shunsuke Sawada, Mikiya Asako, Akihiko Nakamura, David Dombrowicz, Keita Utsunomiya, Tanigawa Noboru, Koichi Tomoda, Hiroshi Iwai
Published 2019-06-01

Eosinophilic Upper Airway Inflammation in a Murine Model Using an Adoptive Transfer System Induces Hyposmia and Epithelial Layer Injury with Convex Lesions

by Akira Kanda, Kenji Kondo, Naoki Hosaka, Yoshiki Kobayashi, Dan Van Bui, Yasutaka Yun, Kensuke Suzuki, Shunsuke Sawada, Mikiya Asako, Akihiko Nakamura, Koichi Tomoda, Yoshiko Sakata, Koji Tsuta, David Dombrowicz, Hideyuki Kawauchi, Shigeharu Fujieda, Hiroshi Iwai
Published 2019-02-01

Cholangiopathy and Biliary Fibrosis in Cyp2c70-Deficient Mice Are Fully Reversed by Ursodeoxycholic AcidSummary

by Jan Freark de Boer, Hilde D. de Vries, Anna Palmiotti, Rumei Li, Marwah Doestzada, Joanne A. Hoogerland, Jingyuan Fu, Anouk M. La Rose, Marit Westerterp, Niels L. Mulder, Milaine V. Hovingh, Martijn Koehorst, Niels J. Kloosterhuis, Justina C. Wolters, Vincent W. Bloks, Joel T. Haas, David Dombrowicz, Bart Staels, Bart van de Sluis, Folkert Kuipers
Published 2021-01-01

Brown adipose tissue monocytes support tissue expansion

by Alexandre Gallerand, Marion I. Stunault, Johanna Merlin, Hannah P. Luehmann, Deborah H. Sultan, Maria M. Firulyova, Virginie Magnone, Narges Khedher, Antoine Jalil, Bastien Dolfi, Alexia Castiglione, Adelie Dumont, Marion Ayrault, Nathalie Vaillant, Jérôme Gilleron, Pascal Barbry, David Dombrowicz, Matthias Mack, David Masson, Thomas Bertero, Burkhard Becher, Jesse W. Williams, Konstantin Zaitsev, Yongjian Liu, Rodolphe R. Guinamard, Laurent Yvan-Charvet, Stoyan Ivanov
Published 2021-09-01