Intermedin suppresses pressure overload cardiac hypertrophy through activation of autophagy.

Intermedin suppresses pressure overload cardiac hypertrophy through activation of autophagy.

Left ventricular hypertrophy is a maladaptive response to pressure overload and an important risk factor for heart failure. Intermedin (IMD), a multi-functional peptide, plays important roles in cardiovascular protection. In this study, we revealed an autophagy-dependent mechanism involved in IMD�...

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Bibliographic Details
Main Authors: Huali Chen, Xue Wang, Mingming Tong, Dan Wu, Sisi Wu, Jiaxiang Chen, Xiaoxiao Wang, Xulei Wang, Yu Kang, Hong Tang, Chaoshu Tang, Wei Jiang
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3667197?pdf=render

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http://europepmc.org/articles/PMC3667197?pdf=render

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