Late morfofunctional alterations of the Sertoli cell caused by doxorubicin administered to prepubertal rats

<p>Abstract</p> <p>Background</p> <p>Doxorubicin is a potent chemotherapeutic drug used against a variety of cancers. It acts through interaction with polymerases and topoisomerase II and free radical production. Doxorubicin activity is not specific to cancer cells and...

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Bibliographic Details
Main Authors: Brilhante Otávio, Okada Fatima K, Sasso-Cerri Estela, Stumpp Taiza, Miraglia Sandra M
Format: Article
Language:English
Published: BMC 2012-09-01
Series:Reproductive Biology and Endocrinology
Subjects:
Rat
Online Access:http://www.rbej.com/content/10/1/79