Duration of Environmental Enrichment Determines Astrocyte Number and Cervical Lymph Node T Lymphocyte Proportions but Not the Microglial Number in Middle-Aged C57BL/6 Mice

Duration of Environmental Enrichment Determines Astrocyte Number and Cervical Lymph Node T Lymphocyte Proportions but Not the Microglial Number in Middle-Aged C57BL/6 Mice

Environmental enrichment (EE) has been shown to modulate behavior and immunity. We recently reported that both short and long-term EE enhance baseline locomotion and alleviate depressive-like behavior, but only long-term EE affects locomotion adversely in a threatening environment and enhances anxie...

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Bibliographic Details
Main Authors: Gaurav Singhal, Julie Morgan, Magdalene C. Jawahar, Frances Corrigan, Emily J. Jaehne, Catherine Toben, Jim Manavis, Anthony J. Hannan, Bernhard T. Baune
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-03-01
Series:Frontiers in Cellular Neuroscience
Subjects:
environmental enrichment
immune
brain
microglia
astrocytes
T cells
Online Access:https://www.frontiersin.org/article/10.3389/fncel.2020.00057/full

Internet

https://www.frontiersin.org/article/10.3389/fncel.2020.00057/full

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