Hypermethylation of genes detected in urine from Ghanaian adults with bladder pathology associated with Schistosoma haematobium infection.

Schistosoma haematobium is associated with chronic bladder damage and may subsequently induce bladder cancer in humans, thus posing a serious threat where the parasite is endemic. Here we evaluated aberrant promoter DNA methylation as a potential biomarker to detect severe bladder damage that is ass...

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Bibliographic Details
Main Authors: Xiaoli Zhong, Sumit Isharwal, Jean M Naples, Clive Shiff, Robert W Veltri, Chunbo Shao, Kwabena M Bosompem, David Sidransky, Mohammad O Hoque
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3601097?pdf=render