The Kynurenine Pathway is a Double-Edged Sword in Immune-Privileged Sites and in Cancer: Implications for Immunotherapy
The term “immune privilege” was originally coined to describe the suppression of inflammatory responses within organs protected by anatomic barriers, ie, the eyes, brain, placenta, and testes. However, cellular and metabolic processes, which orchestrate immune responses, also control inflammation wi...
Main Authors: | Jean-Pierre Routy, Bertrand Routy, Gina M. Graziani, Vikram Mehraj |
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Format: | Article |
Language: | English |
Published: |
SAGE Publishing
2016-01-01
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Series: | International Journal of Tryptophan Research |
Online Access: | https://doi.org/10.4137/IJTR.S38355 |
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