The Kynurenine Pathway is a Double-Edged Sword in Immune-Privileged Sites and in Cancer: Implications for Immunotherapy

The term “immune privilege” was originally coined to describe the suppression of inflammatory responses within organs protected by anatomic barriers, ie, the eyes, brain, placenta, and testes. However, cellular and metabolic processes, which orchestrate immune responses, also control inflammation wi...

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Bibliographic Details
Main Authors: Jean-Pierre Routy, Bertrand Routy, Gina M. Graziani, Vikram Mehraj
Format: Article
Language:English
Published: SAGE Publishing 2016-01-01
Series:International Journal of Tryptophan Research
Online Access:https://doi.org/10.4137/IJTR.S38355