Relationship between the FTO Genotype and Early Chronic Kidney Disease in Type 2 Diabetes: The Mediating Role of Central Obesity, Hypertension, and High Albuminuria

Introduction: Single nucleotide polymorphisms (SNP) in the fat mass and obesity-associated (FTO) gene have been associated with type 2 diabetes (T2D) and its complications. The aim of the present research was to investigate which and how (directly or indirectly) clinical and metabolic variables medi...

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Bibliographic Details
Main Authors: Júlia Marchetti, Karla P. Balbino, Helen Hermana M. Hermsdorff, Leidjaira L. Juvanhol, José Alfredo Martinez, Thais Steemburgo
Format: Article
Language:English
Published: Karger Publishers 2021-06-01
Series:Lifestyle Genomics
Subjects:
Online Access:https://www.karger.com/Article/FullText/516118