Delivery of melittin-loaded niosomes for breast cancer treatment: an in vitro and in vivo evaluation of anti-cancer effect

Delivery of melittin-loaded niosomes for breast cancer treatment: an in vitro and in vivo evaluation of anti-cancer effect

Abstract Background Melittin, a peptide component of honey bee venom, is an appealing candidate for cancer therapy. In the current study, melittin, melittin-loaded niosome, and empty niosome had been optimized and the anticancer effect assessed in vitro on 4T1 and SKBR3 breast cell lines and in vivo...

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Main Authors: Farnaz Dabbagh Moghaddam, Iman Akbarzadeh, Ehsan Marzbankia, Mahsa Farid, Leila khaledi, Amir Hossein Reihani, Mehrnoosh Javidfar, Pejman Mortazavi
Format: Article
Language:English
Published: BMC 2021-06-01
Series:Cancer Nanotechnology
Subjects:
Breast cancer
Immunohistochemistry
Melittin
Nano-niosome
Renal and liver enzymes
Online Access:https://doi.org/10.1186/s12645-021-00085-9

Internet

https://doi.org/10.1186/s12645-021-00085-9

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