Respiratory mechanics do not always mirror pulmonary histological changes in emphysema

OBJECTIVE: To verify the accordance of functional and morphometric parameters during the development of emphysema. METHODS: BALB/c mice received a nasal drop of either papain or saline solution and were studied after 1, 3, 15, 28, and 40 days. Functional parameters, such as airway resistance, tissue...

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Bibliographic Details
Main Authors: Adriana Martins Anciaes, Clarice Rosa Olivo, Carla Máximo Prado, Keila H. Kagohara, Tatiana da Silva Pinto, Henrique T. Moriya, Thais Mauad, Mílton de Arruda Martins, Fernanda Degobbi Tenorio Quirino dos Santos Lopes
Format: Article
Language:English
Published: Faculdade de Medicina / USP 2011-01-01
Series:Clinics
Subjects:
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1807-59322011001000020