Mesenchymal stem cells decrease blood–brain barrier permeability in rats with severe acute pancreatitis

Mesenchymal stem cells decrease blood–brain barrier permeability in rats with severe acute pancreatitis

Abstract Background Impairment of the blood–brain barrier (BBB) could result in secondary cerebral edema and life-threatening pancreatic encephalopathy in patients with severe acute pancreatitis (SAP). Mesenchymal stem cells (MSCs) have been widely adopted in clinical research because of their pleio...

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Bibliographic Details
Main Authors: Ronggui Lin, Ming Li, Meiqin Luo, Tianhong Teng, Yu Pan, Heguang Huang
Format: Article
Language:English
Published: BMC 2019-06-01
Series:Cellular & Molecular Biology Letters
Subjects:
Severe acute pancreatitis
Blood–brain barrier
Mesenchymal stem cell
Inflammatory response
Endothelial cell
Online Access:http://link.springer.com/article/10.1186/s11658-019-0167-8

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http://link.springer.com/article/10.1186/s11658-019-0167-8

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