Acetylation by the transcriptional coactivator Gcn5 plays a novel role in co-transcriptional spliceosome assembly.
In the last several years, a number of studies have shown that spliceosome assembly and splicing catalysis can occur co-transcriptionally. However, it has been unclear which specific transcription factors play key roles in coupling splicing to transcription and the mechanisms through which they act....
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
| Published: |
Public Library of Science (PLoS)
2009-10-01
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| Series: | PLoS Genetics |
| Online Access: | http://europepmc.org/articles/PMC2752994?pdf=render |