Quality evaluation of methyl binding domain based kits for enrichment DNA-methylation sequencing.

Quality evaluation of methyl binding domain based kits for enrichment DNA-methylation sequencing.

DNA-methylation is an important epigenetic feature in health and disease. Methylated sequence capturing by Methyl Binding Domain (MBD) based enrichment followed by second-generation sequencing provides the best combination of sensitivity and cost-efficiency for genome-wide DNA-methylation profiling....

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Bibliographic Details
Main Authors: Tim De Meyer, Evi Mampaey, Michaël Vlemmix, Simon Denil, Geert Trooskens, Jean-Pierre Renard, Sarah De Keulenaer, Pierre Dehan, Gerben Menschaert, Wim Van Criekinge
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/23554971/pdf/?tool=EBI

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https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/23554971/pdf/?tool=EBI

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