Insecticide resistance in Anopheles gambiae from the northern Democratic Republic of Congo, with extreme knockdown resistance (kdr) mutation frequencies revealed by a new diagnostic assay

Insecticide resistance in Anopheles gambiae from the northern Democratic Republic of Congo, with extreme knockdown resistance (kdr) mutation frequencies revealed by a new diagnostic assay

Abstract Background Mutations in the voltage-gated sodium channel at codon 1014 confer knock-down resistance (kdr) to pyrethroids in a wide range of insects. Anopheles gambiae exhibits two mutant alleles at codon 1014, serine and phenylalanine; and both are now widespread across Africa. Existing scr...

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Bibliographic Details
Main Authors: Amy Lynd, Ambrose Oruni, Arjen E. van’t Hof, John C. Morgan, Leon Bwazumo Naego, Dimitra Pipini, Kevin A. O’Kines, Thierry L. Bobanga, Martin J. Donnelly, David Weetman
Format: Article
Language:English
Published: BMC 2018-11-01
Series:Malaria Journal
Online Access:http://link.springer.com/article/10.1186/s12936-018-2561-5

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http://link.springer.com/article/10.1186/s12936-018-2561-5

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