Bio-ModelChecker: Using Bounded Constraint Satisfaction to Seamlessly Integrate Observed Behavior With Prior Knowledge of Biological Networks

The in silico study and reverse engineering of regulatory networks has gained in recognition as an insightful tool for the qualitative study of biological mechanisms that underlie a broad range of complex illness. In the creation of reliable network models, the integration of prior mechanistic knowl...

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Bibliographic Details
Main Authors: Hooman Sedghamiz, Matthew Morris, Travis J. A Craddock, Darrell Whitley, Gordon Broderick
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-03-01
Series:Frontiers in Bioengineering and Biotechnology
Subjects:
Online Access:https://www.frontiersin.org/article/10.3389/fbioe.2019.00048/full